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Product introduction
Warfarin is a kind of coumarin anticoagulants, mainly be used to prevent and treat the thromboembolic disease. Because of its good curative effect and low price, it has been widely used in clinic. However, Warfarin's dose window of treatment is very narrow. According to the Adverse Events Reporting System of FDA, Warfarin is one of the 10 drugs that caused the most serious adverse events. Warfarin's clinical application is just like walking a tightrope. Overdose will cause excessive anticoagulation to lead to hemorrhage because of excessive anticoagulant, while low dose will lead to embolism because of inadequate anticoagulant. The individual disparities of warfarin's dosage demand are high, and the difference of stable dosage between individuals can reach dozens of times.
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